2024 국내 paclitaxel resistance a549

국내 paclitaxel resistance a549

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August undefined, 2024

WebFeb 24, 2024 · Human non-small cell lung cancer cell line (A549), and paclitaxel-resistant A549 (A549/T) cell line was purchased from iCell Biosciences Inc. (Shanghai, China). Both A549/T and A549 cell lines … WebJan 24, 2024 · Unlike common chemotherapeutic drugs such as paclitaxel and cisplatin, cancer cells did not develop acquired resistance to COTI-2. Finally, tumor cells resistant to chemotherapeutic agents (cisplatin, paclitaxel, and 5-FUdR) exhibited no or little cross-resistance to COTI-2.

Cisplatin-resistant lung cancer cell–derived exosomes increase ...

WebThis study aimed to investigate the effect of apatinib on the reversal of paclitaxel (PTX) resistance in A549 lung cancer cells (A549/PTX) and related mechanisms. Materials … tp link bouygues

Cisplatin-resistant A549 non-small cell lung cancer cells can be ...

WebPTX-resistant (A549- and PC-3-PacR) cells were developed to have transient cross-resistance to 5-fluorouracil (PacR/5-FU), docetaxel (PacR/DCT), and cisplatin (PacR/CIS) by culturing PTX-... WebEstablishment of A549 paclitaxel-resistant cells in vivo. (a) A suspension of A549 cells was injected subcutaneously into the flank of a nude mouse. When the average tumor volume … WebA549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1] tp link bluetooth treiber windows 11

Establishment of A549 paclitaxel-resistant cells in vivo.

Modulation of paclitaxel resistance by annexin IV in human

WebAug 1, 2024 · (C) A549 cells were treated with different concentration of cisplatin for 12 h, 24 h and 48 h, and western blot determined the expression level of CREB. At least three independent experiments were performed. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control. (TIF 11383 kb) 13046_2024_1299_MOESM2_ESM.tif(11M) WebMar 4, 2024 · These changes in mitochondria are closely related to anti-tumor drug resistance. In this study, we used the lung adenocarcinoma cell line A549 and its … tp-link bluetooth ub500WebMay 25, 2010 · The paclitaxel-resistant A549-Taxol cell line was established as previously reported. Briefly, the cell lines were selected to be paclitaxel resistant by continuous … tp link bluetooth usb not working

"WebDec 8, 2024 · The human non-small cell lung cancer cell line A549 and the paclitaxel-resistant cell line A549/Taxol were donated by Prof. Yang from Qiqihar Medical College. All the cells were cultured in RPMI-1640 cell culture medium (Solarbio Science and Technology Co., Ltd., Beijing, China) at 37°C and 5% CO 2. " - 국내 paclitaxel resistance a549

국내 paclitaxel resistance a549

The Challenging Treatment of Cisplatin-Resistant Tumors: State …

WebFig. 1: Anti-tumor Effects of Paclitaxel on SC A549 NSCLC Tumors Fig. 2: Anti-tumor Effects of Docetaxel, Bevacizumab or the Combination on SC A549 NSCLC Tumors. At … WebSep 7, 2024 · SOX2 regulates paclitaxel resistance of A549 non‑small cell lung cancer cells via promoting transcription of ClC‑3 . Authors Youwei Huang 1 , Xiangyu Wang 1 , …

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WebNov 29, 2024 · Background Cisplatin plus pemetrexed combination therapy is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer (NSCLC). However, advanced NSCLC has a 5-year survival rate of below 10%, which is mainly due to therapy resistance. We previously showed that the NSCLC cell … WebOne commonly used line is A549, an epithelial carcinoma derived from a 58 year old male patient, known to be KRAS mutant and EGFR wild type. Lung cancer is the leading cause of cancer-related deaths in the world with non-small cell lung cancer (NSCLC) making up about 85% of all lung cancer cases.

WebAbstract Objective To investigate the effect of the SMAC gene on paclitaxel sensitivity and cellular activity in lung adenocarcinoma cells based on the caspase-3/Bcl-2/Bax signaling pathway. Methods A paclitaxel-resistant cell line A549/Taxol was established for lung adenocarcinoma, and the cells were divided into four following groups: pcDNA-NC … WebHDAC activity and function in paclitaxel-resistant NSCLC cells. (a) The effect of paclitaxel on the cell viability of A549 and A549/T cells. The cells were treated with various...

WebThe cellular uptake, intracellular nanoparticle trajectory, and subsequent cellular events were evaluated after treatment with various PLGA nanocomplexes in human lung cancer A549 cells and A549-derived paclitaxel-resistant A549/T12 cell lines with -tubulin mutation.Results: A549 and A549/T12 cells contain constitutively activated Stat3, and ... WebFeb 16, 2024 · The paclitaxel-resistant strain A549-T was established from the parental cell lines by step-dose selection in vitro over six months. We carried out single-cell …

WebThe combination of conventional cytotoxic drugs has been a plausible strategy for overcoming paclitaxel resistance. Herein, we investigated the cytotoxic effects and underlying mechanism of LSS-11, a novel naphthalimide derivative-based topoisomerase inhibitor, in paclitaxel-resistant A549 (A549/T) lung cancer cells. LSS-11 enhanced cell …

WebApr 1, 2024 · All four active compounds, with IC 50 values ranging from 0.002 to 0.91 μM, had better inhibitory activities against A549/Taxol cells than paclitaxel (IC 50 = 1.80 μM). Among them, cucurbitacin E (IC 50 = 0.002 μM) is the most active. Further studies are needed to evaluate their in vivo antitumor activities and to clarify their mechanisms. tp link bluetooth stickWebDosis paclitaxel yang diberikan oleh dokter tergantung pada kondisi kesehatan dan luas permukaan tubuh (LPT) pasien. Secara umum, dosis paclitaxel untuk orang dewasa … tplink bluetooth 認識しないhttp://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2024.22.1114 tplink bouygues telecomWebJun 9, 2024 · Figure 3 B showed that IC50 values for paclitaxel in A549 and A549/PA cells were 1.23 ± 0.14 and 7.03 ± 0.32 μmol/L, respectively, indicating much higher values for A549/PA cells, whose resistance index (RI) was 5.02. A549/PA cells showed more powerful resistance to paclitaxel ( P < 0.05). thermosflasche rotpunktWebJan 2, 2024 · Farmakokinetik. Paclitaxel dilaporkan memiliki farmakokinetik nonlinear, terutama jika diberikan melebihi 3 jam. Konsentrasi plasma maksimum dan area under … thermosflasche patroneWebPaclitaxel resistance in human A549, DU-145, H1299, H1993, H292, H358, H460, LNCaP clone FGC, and PC-3 cell lines and mouse LLC1 cell line and epothilone B resistance in … tp-link bluetooth usbWebOct 6, 2024 · PTX resistance is one of the main obstacles for the clinical use of PTX. 22 Three PTX-resistant sublines, A549-P, A549-PS, and A549-S, were derived from human A549 cells, which had different biological characteristics including morphology and doubling time (data not shown). tplink bluetooth ドライバー