網頁Welcome to the DepMap Portal! The goal of the Dependency Map (DepMap) portal is to empower the research community to make discoveries related to cancer vulnerabilities by providing open access to key cancer dependencies analytical and visualization tools. Use this portal to: DISCOVER genetic and pharmacological dependencies 網頁The CCLE is made possible through a collaboration between the Broad Institute, the Novartis Institutes for Biomedical Research, and the Genomics Institute of the Novartis Research Foundation. Data from the CCLE is available on the CGC via a public project , which acts as a repository for data as well as for examples of specific analyses and the …
A tool for discovering drug sensitivity and gene expression associations in cancer cells …
網頁2024年4月6日 · To our knowledge, eccDNAdb is the first database in the eccDNA research field. It is expected to provide insight for novel cancer therapies. Background Nuclear … 網頁2024年5月2日 · GEMiCCL integrated three genomic resources for cell lines—COSMIC, CCLE, and NCI60. Figure 1 shows data types and statistics for each source database. … problems with gdp
CCLE data
Cancer cell lines are the most commonly used models for studying cancer biology, validating cancer targets and for defining drug efficacy. Prior to the CCLE, cell line investigations were limited to a few commonly used cell lines or at most the 60 cell lines of the NCI60 panel. 查看更多內容 Initiated in January 2008, the overarching goals of this collaboration were: 1) to conduct a detailed genetic and pharmacologic … 查看更多內容 Phase II of the CCLE project expanded on the original characterizations by applying the emerging Next-Gen sequencing to further expand and refine the characterization … 查看更多內容 As characterization of cell lines at the level of nucleic acids reached new levels of completeness we continued to strive towards an … 查看更多內容 網頁2024年2月20日 · Special Issue Information. Dear Colleagues, Colorectal cancer (CRC) is the most frequent cancer and the third most common cause of cancer-related mortality worldwide. A high number of patients with CRC have metastases already at diagnosis, and metastatic CRC is mainly an incurable disease. CRC is considered a heterogeneous … 網頁2024年9月12日 · Background More than 11,000 laboratories and companies developed their own next-generation sequencing (NGS) for screening and diagnosis of various diseases including cancer. Although inconsistencies of mutation calls as high as 43% in databases such as GDSC (Genomics of Drug Sensitivity in Cancer) and CCLE (Cancer Cell Line … regional training center 9 logo