2024 Tmed10 cell

Tmed10 cell

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August undefined, 2024

WebApr 30, 2024 · In the cell, TMED10 localizes on the endoplasmic reticulum (ER)-Golgi intermediate compartment and directs the entry of cargoes into this compartment. … WebIRef Intact Interaction: TMED10 — TMED2 (physical association, anti tag coimmunoprecipitation) Bonnon et al., J Cell Sci 2010 * IRef Intact Interaction : Complex of TMED2-SURF4-TMED10-TMED2-TMED10-SURF4-TMED2-SURF4-TMED10 (association, anti bait coimmunoprecipitation) Mitrovic et al., Mol Biol Cell 2008

Unconventional secretion: cargo channeling by TMED10

WebMar 21, 2024 · TMED10 (Transmembrane P24 Trafficking Protein 10) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification … WebJan 10, 2024 · Virus packaging for lnc-TMED10-2 (ie. lentivirus, AAV, adenovirus, MMLV, MSCV, baculovirus) Custom and pre-made pooled libraries (ie. CRISPR, shRNA, barcode) BAC recombineering for lnc-TMED10-2; Virus packaging for lnc-TMED10-2 CRISPR vectors (ie. lentivirus, AAV, adenovirus) Stable cell line generation for lnc-TMED10-2; mRNA … how to listen to voicemail on att home phone

Unconventional secretion: cargo channeling by TMED10

WebHuman cell lines. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. TMED10. WebHuman TMED10 (TMP21) knockout HEK-293T cell line Parental Cell Line HEK293T Organism Human Mutation description Knockout achieved by using CRISPR/Cas9, Homozygous: 2 bp insertion in exon 1 Passage number <20 Knockout validation Sanger Sequencing, Western Blot (WB) Tested applications Suitable for: WB more details … WebJul 28, 2015 · The following gRNA sequences were designed by Feng Zhang’s laboratory at the Broad institute* to uniquely target the Tmed10 gene within the house mouse genome. These gRNA sequences are for use with WT SpCas9, or as crRNA for use with WT SpCas9 protein, to introduce a DSB for genome editing. how to listen to voice mail

RAB21 interacts with TMED10 and modulates its localization and ...

Tmed10 cell

TMED10 protein expression summary - The Human …

WebMar 10, 2024 · Tmed10 protein, mouse Transforming Growth Factor beta Vesicular Transport Proteins Protein-Serine-Threonine Kinases Receptor, Transforming Growth Factor-beta Type I Receptor, Transforming Growth Factor-beta Type II TGFBR1 protein, human Tgfbr1 protein, mouse WebImmunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using TMED10 antibody (67876-1-Ig, Clone: 3B11F9 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG (H+L). Save time and replace your secondary antibodies with our FlexAble Antibody Labeling Kits.

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WebJun 5, 2024 · Cytomegalovirus gp40/m152 Uses TMED10 as ER Anchor to Retain MHC Class I Highlights • MCMV gp40 retains MHC class I in the ER • The p24 protein TMED10 binds to gp40 • TMED10 is required for gp40-mediated retention of MHC class I • Viral exploitation of the p24 proteins abolishes cell surface expression of MHC class I Summary WebTransfer the cell suspension (0.8 mL) to a 15 mL/50 mL conical sterile polypropylene centrifuge tube containing 8.4 mL pre-warmed culture medium, wash vial with an …

WebThe family is also known as EMP24/GP25L/p24 family and TMP21-like proteins. The latter naming was after transmembrane emp24 domain-containing protein 10 that was found in … WebOct 10, 2024 · TMED10 belongs to a family of type I transmembrane (TM) proteins with a large domain and a short cytosolic tail ( Emery et al., 2000; Gommel et al., 1999 ). TMED …

WebIn addition, TMED10 was found to be crucial for virus-induced plasma membrane blebbing and phosphatidylserine-induced macropinocytosis, presumably by regulating the cell surface expression of the TAM receptor Axl.IMPORTANCE Poxviruses are large DNA viruses that can infect a wide range of host species. WebGene summary (Entrez)i. Useful information about the gene from Entrez. This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. …

WebMar 29, 2024 · The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. The AD-associated protein TMED10 negatively regulates autophagy by inhibiting ATG4B …

WebMouse-over function shows protein score for analyzed cell types in a selected tissue. To access image data click on tissue name or bar. ... TMED10 is part of cluster 29 Non-specific - Vesicular transport with confidence i 1 331 genes in cluster Go to interactive expression cluster page. 15 nearest ... how to listen to voicemail on avaya phoneWebJun 24, 2024 · Here, this study reports that TMED proteins play a critical role in the ER stress-associated UPS of transmembrane proteins. The gene silencing results reveal that TMED2, TMED3, TMED9 and TMED10 are involved in the UPS of transmembrane proteins, such as CFTR, pendrin and SARS-CoV-2 Spike. joshua rogers attorneyWebMar 10, 2024 · The physiological interaction between TMED10 and ALK5 prompted us to examine their subcellular colocalization. When human embryonic retinoblast 911 cells were transfected with both TMED10 and ALK5, both of them could be seen mainly in the cytosol (Fig. 1F, upper panels), because both proteins are synthesized in the rough endoplasmic … how to listen to voicemail on iphone 8WebApr 15, 2024 · Two such proteins, TMED2 and TMED10, were found to specifically contribute to the influence of CDR1as on cell proliferation. CDR1as may regulate these two TMED … how to listen to voicemail on iphone 14WebIn the cell, TMED10 localizes on the endoplasmic reticulum (ER)-Golgi intermediate compartment and directs the entry of cargoes into this compartment. Furthermore, cargo … how to listen to voicemail on vtech dect 6.0WebShowing subcellular location of TMED10 (p23, P24(DELTA), p24d1, p24delta1, TMP21). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. ... Cell lines ordered by organ of phenotypic resemblance. how to listen to voicemail on o2WebTo explore the molecular mechanisms of autophagy, we performed a cell-based functional screening with SH-SY5Y cells stably expressing GFP-LC3, using an siRNA library and … joshua rosenthal md ent